Table 7.

Training and validation tests in cohort 2

	Training set (n = 260, CRC/healthy = 128/132)			Validation set (n = 260, CRC/healthy = 132/128)
	AUC	Formula of probability	Cutoff	Sen	Spe	PPV	NPV	FPR	FNR
FOBT	0.6791	p = exp(−0.6371 + 1.5953*Stool OB)	0.7228	0.5833	0.7891	0.7404	0.6474	0.2109	0.4167
PlGF	0.6713	p = exp(−1.2150 + 0.0953*PlGF)	0.4553	0.6591	0.4844	0.5686	0.5794	0.5156	0.3409
Combined	0.7729	p = exp(−1.9485 + 1.6879*Stool OB + 0.1020*PlGF)	0.5263	0.5985	0.7344	0.6991	0.6395	0.2656	0.4015