Figure 1.
The establishment of a cisplatin‐resistant lung cancer cell line. A, The morphology of parental A549 cells and A549/CDDP cells (magnification, ×100). B, Phalloidine stain the cytoskeleton of parental A549 cells and A549/CDDP cells (magnification, ×200). C, The inhibition ratio of cells treated with different concentration of CDDP and (D) the IC50 value of these cells; *P < 0.01 vs A549 cells. Data are means ± SD from three independent experiments. E, The invasion ability of A549 and A549/CDDP cells; *P < 0.01 vs A549 cells. Data are means ± SD from three independent experiments