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PI3K/AKT signaling contributes to the miR‐4286‐mediated malignant phenotype of NSCLC cells via PTEN. (A, B) PTEN mRNA expression in NSCLC cells transfected with miR‐4286 mimics or inhibitor and the control cells transfected with miR‐NC. (C, D) The A549 and H226 cells were treated with miR‐4286 mimics/the miR‐4286 suppressor or not for 72 h, respectively. The expression levels of p‐AKT, AKT, cyclin D1, and Snail were analyzed by western blotting. * P < 0.05; ** P < 0.01; *** P < 0.001
