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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Am J Surg Pathol. 2018 Jul;42(7):855–865. doi: 10.1097/PAS.0000000000001053

TABLE 2.

Multiple Logistic Regression Model for Histologic Features

Variables Coefficient (β) SE Wald (χ2) Significance Odds Ratio 95% CI
Nuclear pleomorphism* 1.449 0.602 5.791 0.016 4.260 1.309–13.871
Cytoplasmic amphophilia 1.395 0.832 2.809 0.094 0.248 0.049–1.267
N:C ≥ 50% 1.012 0.599 2.851 0.091 2.751 0.850–8.904
Architecture: solid 1.304 0.939 1.926 0.165 3.683 0.584–23.225
Architecture: scirrhous 1.021 0.713 2.054 0.152 2.777 0.687–11.222
Architecture: acinar 0.736 0.878 0.703 0.402 2.088 0.374–11.671
Macronucleoli 0.570 0.622 0.841 0.359 1.768 0.523–5.979
Mitotic index 0.337 0.596 0.320 0.571 1.401 0.436–4.507
CK19 labeling −1.229 1.350 0.828 0.363 0.293 0.021–4.127
Intratumoral steatosis −0.486 0.706 0.473 0.492 0.615 0.154–2.457
Intercept −3.477 0.750
*

Nuclear pleomorphism is a statistically significant independent predictor of tumor recurrence after transplant.

95% CI indicates 95% confidence interval for estimated odds ratio; intercept, mathematical constant;

N:C, nuclear-to-cytoplasmic ratio; Wald, Wald test statistic.