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. 2016 Mar 30;36(13):3777–3788. doi: 10.1523/JNEUROSCI.0451-15.2016

Figure 4.

Figure 4.

CCL2 and other inflammatory genes are upregulated in the hippocampus of LPS-treated epileptic mice. qRT-PCR validation of microarray experiments; plots represent the mRNA expression of 9 inflammatory genes differentially expressed (upregulated) in the hippocampus of LPS-treated epileptic mice. Values are plotted as the fold increase in LPS- versus saline-treated chronically epileptic mice (LPS/SAL ratio). CCL2 mRNA was 10-fold upregulated in LPS-treated epileptic hippocampus 4 h after LPS administration, with a significant decrease of 44.5% at 24 h (two-way ANOVA followed by Tukey's test, p < 0.001). *p < 0.05; ***p < 0.001.