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. 2016 May 4;36(18):4993–5002. doi: 10.1523/JNEUROSCI.0135-16.2016

Figure 1.

Figure 1.

Q175 mice display compromised motivation and reward-evoked dopamine release in the NAc. A, Representative cumulative response record during a PR session in the two genotypes. Vertical ticks demarcate reward receipt. B, Mean (+SEM) breakpoints in WT (n = 8) and Q175 (n = 12) mice. C, Mean dopamine concentration ([DA]; +SEM) across all trials. D, Mean of the single, largest dopamine concentration increase (+SEM) in each animal. **p < 0.01, ***p < 0.001.