Figure 5.

Rate remapping is measured with the DI. The DI, defined as the difference in the number of spikes fired per lap in the two directions divided by the sum of the number of spikes of a neuron, is plotted for each recording day and pooled over animals. The mean and SEM of the DI in the different direction comparison (red, A vs B and A′ vs B′) and same direction comparison (blue, A vs A′ and B vs B′) over all animals for each lap are plotted (Wilcoxon rank-sum test, one-tailed, day 1, p = 0.004, days 2–5, p < 0.0001). For day 1, the DIs in the first two sessions (A vs B) were not significantly different from the A versus A′ comparison, but the DI increased over laps, as shown previously (Navratilova et al., 2012). By sessions 3 and 4 (A′ vs B′), the DIs were significantly different from the same direction comparison. On Days 2–5, the DIs in the first 2 sessions did not differ from the DIs in the last 2 sessions and thus were plotted together for clarity. Laps are cut off at the worst-performing animal on that day.