Table 1.

Synergistic effect on β-catenin overexpression and Notch1 deletion on Sox²⁺ SCs proliferation and HCs generation

	Control (n = 4)	β-cat-OE (n = 3)	Notch1-KO (n = 4)	β-cat-OE Notch1-KO (n = 4)
EdU+Sox2+ SCs/100 μm of sensory region
Apex	0	44.67 ± 7.13	50 ± 2.52	81.00 ± 5.12
Mid	0	9.00 ± 2.31	2.33 ± 0.33	37.75 ± 8.86
Base	0	0	2.00 ± 1.16	5.50 ± 1.71
EdU+Sox2+ SCs/100 μm of GER
Apex	0	45.67 ± 3.76	39.67 ± 2.03	64.00 ± 5.770
Mid	0	26.67 ± 4.10	4.67 ± 1.20	40.25 ± 4.99
Base	0	2.67 ± 0.67	0	19.25 ± 3.40
Sox2+ SCs/100 μm of sensory region
Apex	79.00 ± 2.08	108.30 ± 4.10	87.33 ± 3.93	128.00 ± 4.06
Mid	80.33 ± 2.60	84.33 ± 2.73	60.67 ± 3.28	93.25 ± 2.32
Base	70.67 ± 3.18	68.33 ± 4.41	72.00 ± 2.08	68.25 ± 3.54
EdU+Myo7a+ HCs/cochlea	0	1.33 ± 0.33	18.50 ± 1.56	27.00 ± 2.59
Myo7a+ HCs/100 μm
Apex	57.33 ± 0.67	50.67 ± 1.85	132.67 ± 2.96	87.67 ± 1.20
Mid	56.33 ± 2.33	55.67 ± 1.45	67.00 ± 3.21	65.67 ± 7.97
Base	50.33 ± 3.18	50.00 ± 4.73	52.67 ± 1.33	45.67 ± 2.19
EdU+Myo7a+/ EdU+ Sox2+
Apex	0	1.30 ± 0.65%	9.97 ± 0.02%	3.86 ± 1.19%