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Ahr-induced expression of Cyp1b1 is dependent on β-catenin, whereas Cyp1a1 transcription is not. qRT-PCR analysis for Cyp1b1 (A) and Cyp1a1 (B) in β-catenin WT and β-catenin KO ECs stimulated with 25 nm TCDD for 7 h in combination with 10 μm CH-223191 (n = 5). Expression levels of β-catenin WT ECs under control conditions were defined as 1 (dashed line). *p < 0.05. **p < 0.01. ***p < 0.001. ns, Not significant. Error bars indicate SEM.
