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. 2016 Aug 24;36(34):8783–8789. doi: 10.1523/JNEUROSCI.1181-16.2016

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Copyright © 2016 the authors 0270-6474/16/368783-07$15.00/0

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Figure 3. — Exogenous NMDA accelerates removal of excess innervation. Left, Examples of multiply innervated (asterisks) and singly innervated end plates in control and NMDA-treated muscles at P8. Scale bar, 50 μm. Right, NMDA-treated muscles at P8 had significantly fewer multiply innervated fibers than control. Open symbols indicate control; filled symbols, treated (EDL: 48 ± 2%, control limb vs 38 ± 4% vs NMDA-treated limb, p = 0.05, n = 8, 9; soleus: 63 ± 2%, control limb vs 49 ± 4%, NMDA-treated limb, p = 0.014, n = 7, 8).