Figure 8.
Gpr17 ablation in adulthood has no effect on myelinogenesis. A, Schematic strategy for the generation of the Gpr17fl/fl mouse strain. B, Immunofluorescent staining for MBP of spinal cord sections from wild-type and Gpr17 cKO mice at P0 (n = 5 animals per genotype). Scale bar, 100 μm. C, Electron microscopic examination of the corpus callosum of wild-type, Gpr17−/−, and Gpr17 cKO mice at 8 weeks of age (n = 5 animals per genotype). Scale bar, 1 μm. D, Immunofluorescent staining using the indicated antibodies of brain sections from wild-type, Gpr17−/−, and Gpr17 cKO mice at 8 weeks of age (n = 5 animals per genotype). Scale bar, 100 μm. Pran, Pranlukast.