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. 2016 Nov 30;36(48):12129–12143. doi: 10.1523/JNEUROSCI.1849-16.2016

Figure 12.

Figure 12.

Enhanced hole-board repetitive behavior and light-dark anxiety-like behavior in Pcp2-Cre;Shank2fl/fl mice. A–D, Increased repetitive behavior of Pcp2-Cre;Shank2fl/fl mice (3–5 months) in the hole-board test (A, B), but normal behavior in Shank2−/− mice (C, D). n = 17 male mice for WT and cKO; n = 12 male for WT and 14 male for KO. *p < 0.05 (Student's t test). **p < 0.01 (Student's t test). E, F, Enhanced anxiety-like behavior of Pcp2-Cre;Shank2fl/fl mice (3–5 months) in the light-dark test (E) but normal behavior in Shank2−/− mice (F). n = 22 male for WT and 20 male for cKO; n = 8 male for WT and 10 male for KO. **p < 0.01 (Student's t test). G, Normal anxiety-like behavior of Pcp2-Cre;Shank2fl/fl mice (3–5 months) in the elevated plus maze test. n = 24 male for WT and cKO. Student's t test.