Figure 1.
Spike generation is controlled by a generator potential (x-axis) along a spiking nonlinearity, resulting in mean firing rates being proportional to the gain, which is represented by the slope of the linear fits (solid lines). Low- and high-spatial-frequency neurons (dots) exhibited a similar firing rate increase during locomotion (Δratehigh == Δratelow) but had different operating points (ratehigh ≪ ratelow). Given this difference, a shift in the operating point of V1 neurons along the spiking nonlinearity between rest and locomotion preferentially enhanced the relative gain of high-spatial-frequency neurons, heightening resolution.