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. 2016 Feb 3;36(5):1456–1470. doi: 10.1523/JNEUROSCI.2390-15.2016

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Copyright © 2016 the authors 0270-6474/16/361456-15$15.00/0

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Figure 1. — 5-HT₃ and P2X2 receptors are coexpressed in neurons of the myenteric plexus. Immunohistochemical detection of 5-HT_3A, 5-HT_3B, and P2X2 subunits in the rat intestinal tract at 4 d postnatal. A, 5-HT_3A (rabbit anti-5-HT_3A antibody; green) and P2X2 (guinea pig anti-P2X2 antibody; red). B, 5-HT_3B (goat anti 5-HT_3B antibody; green) and P2X2 (rabbit anti-P2X2 antibody; red). Both 5-HT₃ subunits colocalize with P2X2R in the same neurons (arrows). mp, Myenteric plexus; lm, longitudinal muscle; cm, circular muscle. Scale bar, 50 μm.