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. 2016 Jan 20;36(3):926–937. doi: 10.1523/JNEUROSCI.1825-15.2016

Figure 4.

Figure 4.

Presence of a locomotor drive potential in thoracic expiratory motoneurons during drug-induced fictive locomotion. A, C, Schematics of the experimental procedure. B, D1, Rhythmic respiratory activity recorded in a thoracic expiratory motoneuron (T8 Mn) and in C4 (inspiratory-like), T8 (mixed inspiratory-expiratory), and left (l) and right (r) L2 (expiratory-like) ventral roots under control saline conditions (B), and during NMA/5-HT application to the lumbar region (D1). Expanded traces are shown in D2. D3, Averaging of membrane potential of a T8 expiratory motoneuron and integrated L2 ventral root activity during 65 cycles of fictive locomotion. D4, Circular plots showing the phase relationships between the onsets of locomotor-related membrane depolarization in the T8 Mn and integrated motor bursts (n = 65) recorded in the ipsilateral (l) L2 ventral root (plot at left), and between integrated motor bursts recorded in left and right L2 ventral roots (plot at right). AP, Action potential; RMP, resting membrane potential.