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. 2016 Jan 13;36(2):506–517. doi: 10.1523/JNEUROSCI.2584-15.2016

Figure 2.

Figure 2.

Effects of KA treatment on induction of seizures in hippocampus and central autonomic nuclei. Change in gamma range frequency (25–45 Hz) in hippocampal EEG and sympathetic nerve recordings every 10 min after 2 mg/kg KA injection. Arrow indicates time of RVLM microinjections and intraperitoneal KA. Dotted arrows indicate the starting points for increase in EEG and/or SNA activity. Induction of seizure activity in sympathetic nerve activity does not start at least until 70 min after KA injection, whereas hippocampal seizure activity starts ∼15–20 min after KA injection followed by an increase in SNA at 25–30 min. Time-dependent increases in hippocampal seizure activity occur up to 110 min after KA injection followed by a fall.