Table 3.
Return of fear
| Site | Cluster size | ZMAX | Coordinates (MNI) |
||
|---|---|---|---|---|---|
| x | y | z | |||
| Left vmPFC | 190 | 4.0471 | −4 | 39 | −15 |
| 3.7893 | −12 | 48 | −14 | ||
| Left amygdala | 56 | 4.0272** | −27 | −8 | −14 |
| Right vmPFC | 65 | 3.9924** | 3 | 32 | −20 |
| Right cerebral white matter (corpus callosum) | 61 | 3.9102 | 8 | 22 | 18 |
| Right anterior cingulate gyrus | 61 | 3.6232 | 10 | 34 | 6 |
| 3.4330 | 8 | 40 | −2 | ||
| Left paracingulate gyrus | 46 | 3.5662 | −6 | 44 | 0 |
During recall, participants in the late wake group showed a stronger differential activation between conditioned and extinguished stimuli compared with neutral stimuli (CS+E > CS−E; each corrected for acquisition). Regions were thresholded at p < 0.001, uncorrected, with 40 voxel minimum cluster size, and determined following anatomical landmarks on the mean T1 image normalized to a DARTEL template.
**Regions were small-volume corrected (pFWE-SVC < 0.01) in the a priori defined regions of interest.