Skip to main content
. 2019 Jun 25;31(5):369–386. doi: 10.1089/ars.2018.7688

FIG. 2.

FIG. 2.

hCVPCs increase angiogenesis and reduce cardiomyocyte apoptosis. (A, B) Representative and quantification of IHC staining for TUNEL+ cardiomyocytes in the border zone of infarcted hearts at day 3 post-MI. n = 5 hearts each. Scale bar, 100 μm. (C) Representative and averaged Western blot analysis for caspase-3 (Cas. 3), cleaved caspase-3 (cCas.3), and GAPDH in the infarct zone of day 3 post-MI hearts. n = 3 hearts each. (D) Immunochemistry staining for CD31+ endothelial cells at day 28 post-MI. n = 4 hearts each. Scale bar, 100 μm. (E) Immunochemistry staining for α-SMA+ blood vessels at day 28 post-MI. n = 4 hearts each. Scale bar, 100 μm. *p < 0.05, **p < 0.01, ***p < 0.001. α-SMA, alpha-smooth muscle actin; BZ, border zone; cTnI, cardiac troponin I; cTnT, cardiac troponin T; DAPI, 4′,6-diamidino-2-phenylindole; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IHC, immunohistochemistry; IZ, infarct zone; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.