TABLE 1.
Characteristics of patients with NASH and controls
| Variable | NASH (n = 9) | Controla (n = 8) | P |
| Females [n (%)] | 5 (55) | 7 (87) | 0.294 |
| Age at sample, years [median (IQR)] | 35.1 (28.2–38.3) | 47.2 (36.6–56.6) | 0.059 |
| BMI, kg/m2 [median (IQR)] | 45.4 (44.3–48.8) | 31.2 (21.1–36.9) | 0.0003 |
| AST,b U/l [median (IQR)] | 28 (25–49) | 29 (21–36) | 0.299 |
| ALT,b U/l [median (IQR)] | 35 (27–65) | 21.5 (16.2–34.2) | 0.102 |
| NAS [n (%)] | |||
| 0 | 0 (0) | 8 (100) | |
| 1 | 0 (0) | 0 (0) | |
| 2 | 0 (0) | 0 (0) | |
| 3 | 3 (33.3) | 0 (0) | |
| 4 | 3 (33.3) | 0 (0) | |
| 5 | 3 (33.3) | 0 (0) | |
| Fibrosis | 5 (55.5) | 0 (0) |
Statistical comparisons were carried out with the use of the Mann-Whitney U test and Fisher’s exact test.
a
The control group includes four bariatric patients undergoing liver biopsy during surgery without NASH and without liver steatosis and patients undergoing partial liver resection due to liver metastasis of (one each) pancreatic carcinoma, rectum carcinoma, and gall bladder carcinoma as well as Ecchinococcus.
b
Normal: <35 females and <50 males.