Fig 6. In silico AWCON knockouts voltage response to current injection.
The stimulation protocol consists in a single 15 pA current step with a duration of 500 ms. The holding current is Ih = 0pA. Each knockout is obtained by suppressing the contribution of the selected current, leaving unchanged the other conductances. In panels A-F we report the response of NCA (A), voltage-gated potassium channels (B and C), voltage-gated calcium channels (D), and calcium-regulated potassium channels (E and F) knockouts.