Fig 9. In silico RMD knockouts voltage response to current injection.
The stimulation protocol consists in a single 10 pA current step with a duration of 50 ms. The holding current is Ih = 0 pA. Each knockout is obtained by suppressing the contribution of the desired current, leaving unchanged the other conductances. In panels A-F we report the response of NCA (A), voltage-gated potassium channels (B and C), voltage-gated calcium channels (D), and calcium-regulated potassium channels (E and F) knockouts.