Table 5. Positively selected genes and the corresponding proteins in different treponemal species and subspecies.

Proteins previously reported as recombinant out of the positively selected proteins are also shown.

Treponema pallidum subspecies	Recombinant proteins	Positively selected proteins
TPA	TprC, G, J, BamA, Mcp-2, TP0136	TprC, F, G, J, L, BamA, Mcp-2 TP0126b, TP0133, TP0136, TP0314, TP0462, TP0515, TP0548, TP0619, TP0733, TP0859, TP0865
TPE	TprI	TprE, F, I TP0126b, TP0133, TP0314, TP0548, TP0619, TP0733, TP0858, TP0859, TP0865
TEN	BamA, Mcp-2, TprL TP0548, TP0856, TP0858	TprL TP0856, TP0858, TP0865