Fig. 5.

Effects of BDNF application to proteins related to synaptic plasticity. Results of western blot analysis of NMDA receptor 1 (NMDA1), NMDA2B, p-CaMKII and p-CREB. There were significant elevations in NMDA1, NMDA2B, p-CaMKII and p-CREB in the BDNF-injected group compared with the PBS-injected group at 4 weeks after cauterization. For the western blot analysis, the PBS-injected group and the BNDF-injected group each included 6 retinas at each time point; total n=48. The bar represents the mean±s.d. and a Student's t-test was used for statistical evaluation. *P<0.05.