Fig. 3.
Relating progenitor cell groups to their original positions in the diencephalon. (A-D) Expression of cell-specific markers on t-SNE plots (left) and on coronal sections of mouse diencephalon (right) at E13.5 (A,B; from Allen Developing Mouse Brain Atlas) and E12.5 (C,D). On t-SNE plots, the cells that express a given marker are shown in red or blue as indicated; those that express both are shown in green and outlined by dashed lines. Cell groups expressing a single marker are indicated by an arrowhead with matching color on both t-SNE plots and sections. (E) t-SNE plots of diencephalic progenitor cell groups. The dashed arrows show developmental trajectories. (F) Schematic of scRNAseq-identified progenitor groups within the diencephalon. BP, basal plate; cTh, caudal thalamus; p2, prosomere 2; RP, roof plate; rPT, rostral pretectum; rTh, rostral thalamus.