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. 2019 May 22;47(W1):W99–W105. doi: 10.1093/nar/gkz411

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Simple ClinVar internal workflow and main module. (A) Information flow overview of the Simple ClinVar web application. The ClinVar database is pre-filtered with the clinvar.pre-filtering.pl script available at our GitHub page (http://github.com/dlal-group/Simple-ClinVar) to generate the ClinVar prefiltered file that is interrogated by the user. Upon query submission, the user interface generated with R software connects with pre-filtered file and UniProt features to deliver a result. (B) Simple ClinVar front page where the user can perform different types of queries.