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. 2019 May 9;47(W1):W482–W489. doi: 10.1093/nar/gkz358

Figure 2.

Figure 2.

The 3D rendition of the heavy chain of antibody drug Avastin (blue color) with antigen VEGF (salmon color) (PDB code: 1BJ1) and interfacial waters (red balls) using AppA. The contact residues of heavy chain of Avastin and VEGF are highlighted in sticks. As seen, the structure (conformations) of the antigen VEGF is mainly composed of beta-sheets.