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. 2019 May 13;47(W1):W283–W288. doi: 10.1093/nar/gkz372

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — iMKT graphical output of an application example. Sampling distribution of α values for protein-coding genes located in regions of high recombination (recombination rate >7 cM/Mb) compared to all protein-coding genes in the genome for (A) the D. melanogaster Raleigh (RAL) population (blue) and the D. melanogaster Zambia (ZI) population (yellow) and (B) the human Utah Residents (CEU) population (blue) and the human Yoruba (YRI) population (yellow). The distribution was calculated by randomly sampling 400 genes 100 times from the two lists of genes with replacement and estimating α in each bin. Polymorphisms with a frequency below 0.05 in the analyzed population were discarded (see main text).