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. 2019 May 4;47(W1):W206–W211. doi: 10.1093/nar/gkz332

Figure 2.

Figure 2.

The performance of Cistrome-GO in solo mode. (A) Evaluation of the performance between Cistrome-GO and other web servers (including GREAT, ChIP-Enrich and Enrichr) on 256 TF ChIP-seq datasets. For each web server, the most significant 5000, 10 000, 15 000, 20 000 and all ChIP-seq peaks were used in the evaluation separately. The MSS score quantifies the similarity between the web server predictions and the standard set of GO terms for each TF. (B) The percentage of the most significant E2F1 ChIP-seq peaks (top 2000, 5000, 10 000 and all peaks separately; ranked by −log10(P-value)) are close (<1 kb) to TSS. (C) The top 10 enriched BP terms for 10 000 E2F1 ChIP-seq peaks using 1 kb as the decay distance. The BP terms indicated by red arrows are those relevant to cell-cycle functions. The color gradient represents the gene number in each GO term.