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Structure of PfRH5ΔNL in Complex with R5.011 and R5.016
(A) Crystal structure of PfRH5ΔNL bound to Fab fragments from R5.011 and R5.016. The top left inset shows a close-up of the R5.011 epitope. The bottom left inset shows PfRH5 as a gray surface with the peptide most protected by R5.011 mAb in a HDX-MS assay in green. R5.011 is overlaid as a faded cartoon.
(B) Overlay of R5.004, R5.011 and R5.016 structures bound to PfRH5ΔNL.
