Figure 7.
R5.011 Increases Parasite Invasion Time
(A) Total time for RBC invasion in the presence of R5.011 or an irrelevant isotype-matched antibody control (α-EBOV).
(B) Time for early invasion (pre-penetration) and late invasion (penetration). Data are presented as box-and-whiskers plots showing the interquartile range and total range overlaid on individual data points. Solid black lines show the mean for each group. 3D7 clone P. falciparum parasites were used. Both mAbs were used at 500 μg/mL and 21 and 22 invasion events were recorded for α-EBOV and R5.011, respectively. ∗∗∗∗p < 0.0001; n.s., non-significant.