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Clinical Trial (VAC057) Volunteer Information and Additional PfRH5 mAb Binding Data, Related to Figure 1
(A) Vaccination details of the three volunteers from which anti-PfRH5FL mAbs were isolated. (B) List of anti-PfRH5 mAb binding properties. Association-rate (Kon), dissociation-rate (Koff) and affinity (KD) are shown. (C) Dot blot showing anti-PfRH5 mAbs binding to parasite-derived PfRH5. PBS, PfRH5FL and a recombinant anti-Ebolavirus IgG1 mAb (α-EBOV) were used as controls.
