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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Acc Chem Res. 2017 Apr 20;50(5):1193–1201. doi: 10.1021/acs.accounts.7b00012

Figure 2.

Figure 2

Representation of the conformational changes in the KD of c-Src KD upon activation. (a) Comparison of the active (yellow) and the inactive (green) conformations. (b) The catalytic (yellow) and the regulatory (red) spines in the active (b) and inactive (c) state of the KD.