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. 2019 Apr 30;10(4):e00020. doi: 10.14309/ctg.0000000000000020

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© 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 5. — Circulating PD-1+ Tfh2 and Tfh17 subsets correlate with disease activity in IgG4-SC/AIP. Disease activity was measured using the IgG4-RI. Correlation plots showing disease activity (DA) (log 10) plotted against the percentage of (a) CXCR5+ Tfh cells, (b) Tfh2 cells, (c) PD-1+ Tfh cells, (d) PD1+ Tfh1 cells, (e) PD1+ Tfh2 cells, and (f) PD1+ Tfh17 cells. Spearman rank correlation and P values as per Figure 2. AIP, autoimmune pancreatitis; IgG4-RI, IgG4-responder index; IgG4-SC, IgG4-related sclerosing cholangitis; PD-1, programmed cell death protein 1; Tfh, T-follicular helper.