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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Alcohol Clin Exp Res. 2019 May 14;43(7):1439–1451. doi: 10.1111/acer.14065

Figure 8. MIF is required for CHOP expression in thapsigargin-treated hepatocytes.

Figure 8

AML-12 murine hepatocytes were treated with VEH (0.05% DMSO) or MIF098 (20 µM) then exposed to thapsigargin (0.1–1.0 µM) for 6h. A) Expression Chop and B) spliced Xbp-1 mRNA was determined by qRT-PCR and normalized to 18S RNA. C) Expression of p-eIF2α and D) CHOP were determined 6h after thapsigargin exposure and normalized to GAPDH. Values are means ± SEM. Values with different superscripts are significantly different, p<0.05