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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Alcohol Clin Exp Res. 2019 May 28;43(7):1510–1518. doi: 10.1111/acer.14081

Table 3:

Annual percent change from 1999/2000 to 2013/2014 and modeled prevalence of use of opioids and sedative-hypnotics overall and by regular drinking status.

Annual Percent Change (95% CI)
Modeled Prevalence (95% CI)
Unadjusted
Adjusteda
1999/2000
2013/2014
Overall
Opioids 2.5 (1.0, 4.0) 3.0 (1.6, 4.4) 5.4 (4.8, 6.2) 7.6 (6.7, 8.7)
Sedative-Hypnotic 3.6 (2.0, 5.3) 3.8 (2.1, 5.5) 4.2 (3.6, 4.9) 6.9 (6.2, 7.7)
 Anxiolytics 2.4 (0.5, 4.3) 2.7 (0.8, 4.7) 3.6 (3.1, 4.3) 5.1 (4.4, 5.9)
 Sleep Meds 9.6 (7.3, 11.9) 9.3 (6.9, 11.8) 0.7 (0.5, 0.9) 2.5 (2.2, 2.9)
Group: Regular Drinking
Opioids 1.4 (−1.2, 4.0)ns 1.9 (−0.7, 4.5)ns 4.3 (3.5, 5.2) 5.2 (4.1, 6.5)
Sedative-Hypnotic 5.3 (2.7, 7.9) 4.6 (2.0, 7.4) 2.9 (2.3, 3.6) 6.0 (4.9, 7.2)
 Anxiolytics 3.7 (0.8, 6.7) 3.4 (0.4, 6.4) 2.3 (1.8, 3.0) 3.9 (3.1, 4.9)
 Sleep Meds 11.2 (6.5, 16.0) 9.9 (5.0, 14.9) 0.6 (0.4, 1.0) 2.8 (2.1, 3.6)
Group: Infrequent Drinking/Abstain
Opioids 3.0 (1.5, 4.5) 3.5 (2.1, 4.9) 6.0 (5.2, 6.9) 9.1 (8.0, 10.3)
Sedative-Hypnotic 3.2 (1.5, 4.9) 3.6 (1.8, 5.3) 4.8 (4.1, 5.6) 7.5 (6.6, 8.5)
 Anxiolytics 2.2 (0.2, 4.3) 2.6 (0.5, 4.8) 4.3 (3.6, 5.1) 5.8 (4.9, 6.8)
 Sleep Meds 8.7 (5.7, 11.9) 8.8 (5.8, 12.0) 0.7 (0.5, 1.0) 2.3 (1.9, 2.8)
a

Models adjusted for sex, race, age, and education.

Notes: (1) regular alcohol drinking defined as consuming alcohol at least 52 times in the past year; (2) infrequent drinking/abstain defined as using alcohol less than 52 times in the past year; (3) opioid and sedative-hypnotic use defined as prescribed use of either medication for 30 days or longer; “ns” indicates not statistically significant with alpha set at 0.05.