Table 1:
Hospitalization Rates in Early Intervention Controlled Trial Treatment Studies
| Study | Country | Number of Participants | Length of Treatment | Hospitalization Rates During Follow-Up Interval | |
|---|---|---|---|---|---|
| Experimental Intervention | Treatment As Usual | ||||
| Sample Size > 100 | |||||
| OPUS (during year 2 of trial1) (11) | Denmark | 243 intervention 193 control2 | 13–24 months | 26% | 39% |
| PIANO (15) | Italy | 272 intervention 172 control | 9 months | 17% | 16% |
| Valencia et al Study 1 (14) | Mexico | 60 intervention 60 control | 6 months | 5.6% | 10% |
| LEO (10) | United Kingdom | 71 intervention 73 control | 15 months | 33% | 51% |
| RAISE-ETP (16) | United States | 223 intervention 181 control | 24 months | 34% | 37% |
| STEP (17) | United States | 60 intervention 57 control | 12 months | 23% | 44% |
| Sample Size < 100 | |||||
| Grawe et al (12) | Norway | 30 intervention 20 control | 24 months | 33% | 50% |
| Valencia et al Study 2 (13) | Mexico | 44 intervention 44 control | 12 month | 5.1% | 10.7% |
| COAST (9) | United Kingdom | 32 intervention 27 control | 12 months | 7 total admissions for 32 participants | 11 total admissions for 27 participants |
1
rates of hospitalization in OPUS for year 1 were 59% with the intervention and 71% with treatment as usual. These rates include the hospitalization at the time of recruitment for participants recruited as inpatients.
2
participants with 2 year follow-up; baseline sample included 263 participants assigned to the intervention and 244 assigned to treatment as usual