Table 5.

Multivariate Models of Associations Between Baseline and Time-Varying Variables and Hospitalization

Model 11
	Hazard Ratio	95% Confidence Interval	Chi-Square2	p-value
One prior hospitalization before baseline versus none	2.02	.97–4.22	3.51	.061
Two prior hospitalizations before baseline versus none	2.55	1.11–5.86	4.84	.028
Three or more prior hospitalizations before baseline versus none	4.42	2.03–9.59	14.09	<.001
Time-varying Positive and Negative Syndrome Scale Positive Factor	1.08	1.02–1.14	7.87	.005
Time-varying days of illegal drug use	1.03	1.00–1.05	4.74	.029
Model 23
	Hazard Ratio	95% Confidence Interval	Chi-Square2	p-value
Duration of Untreated Psychosis > 74 weeks	1.78	1.14–2.79	6.41	.011
One prior hospitalization before baseline versus none	2.59	1.18–5.67	5.67	.017
Two prior hospitalizations before baseline versus none	3.42	1.42–8.21	7.53	.006
Three or more prior hospitalizations before baseline versus none	5.67	2.51–12.83	17.35	<.001
Time-varying days of illegal drug use	1.03	1.01–1.05	5.96	.015
Time-varying Brief Evaluation of Medication Influences and Beliefs	.82	.67–.99	4.15	.042

¹Model from backward selection of variables (frailty model with site). Variables entered into the analysis: baseline variables were duration of untreated psychosis greater than 74 weeks and number of prior hospitalizations; time-varying variables were Positive and Negative Syndrome Scale Positive and Excited factors, Calgary Depression Scale for Schizophrenia, days of illegal drug use, Adherence Estimator Risk scores and being a student or working

²df for all Chi-Square analyses =1

³Model from backward selection of variables (frailty model with site). Variables entered into the analysis: baseline variables were duration of untreated psychosis greater than 74 weeks and number of prior hospitalizations; time-varying variables were days of illegal drug use, Longitudinal Brief Evaluation of Medication Influences and Beliefs, Well Being Scale total score and being a student or working