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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Head Trauma Rehabil. 2019 Jul-Aug;34(4):E1–E10. doi: 10.1097/HTR.0000000000000465

Table 2:

Prevalence of Medical Comorbidities Listed by Body System

Before TBI Same Time / After TBI Ever
X / N Percent 95% CI X / N Percent 95% CI X / N Percent 95% CI
Cardiovascular
Hypertension 46/394 11.7 (8.5, 14.9) 79/394 20.1 (16.1, 24.0) 133/402 33.1 (28.5, 37.7)
Congestive Heart Failure 3/401 0.8 (0.0, 1.6) 5/401 1.2 (0.2, 2.3) 9/402 2.2 (0.8, 3.7)
Myocardial Infraction/Heart Attack 8/401 2.0 (0.6, 3.4) 7/401 1.7 (0.5, 3.0) 16/402 4.0 (2.1, 5.9)
Other Heart Conditions 16/398 4.0 (2.1, 6.0) 20/398 5.0 (2.9, 7.2) 40/402 10.0 (7.0, 12.9)
Stroke 2/401 0.5 (0.0, 1.2) 13/401 3.2 (1.5, 5.0) 16/402 4.0 (2.1, 5.9)
High Blood Cholesterol 31/398 7.8 (5.1, 10.4) 68/398 17.1 (13.4, 20.8) 101/401 25.3 (21.0, 29.5)

Endocrine
Diabetes 10/402 2.5 (1.0, 4.0) 35/402 8.7 (5.9, 11.5) 45/402 11.2 (8.1, 14.3)
Goiter 0/401 0.0 - 1/401 0.2 (0.0, 0.7) 1/401 0.2 (0.0, 0.7)
Other Thyroid Disease 10/401 2.5 (1.0, 4.0) 11/401 2.7 (1.1, 4.3) 21/401 5.2 (3.0, 7.4)

Gastrointestinal
Liver Disease 9/402 2.2 (0.8, 3.7) 10/402 2.5 (1.0, 4.0) 19/402 4.7 (2.6, 6.8)

Genitourinary
Kidney Stones 13/400 3.3 (1.5, 5.0) 13/400 3.3 (1.5, 5.0) 26/400 6.5 (4.1, 8.9)

Musculoskeletal & Rheumatologic
Rheumatoid Arthritis 8/401 2.0 (0.6, 3.4) 21/401 5.2 (3.0, 7.4) 30/402 7.5 (4.9, 10.0)
Osteoarthritis 18/400 4.5 (2.5, 6.5) 38/400 9.5 (6.6, 12.4) 58/402 14.4 (11.0, 17.9)
Fractures (Hip/Wrist/Spine) 19/400 4.8 (2.7, 6.8) 73/400 18.3 (14.4, 22.1) 93/401 23.2 (19.0, 27.3)
Back Pain 30/399 7.5 (4.9, 10.1) 87/399 21.8 (17.7, 25.9) 119/401 29.7 (25.2, 34.2)
Osteoporosis 4/401 1.0 (0.0, 2.0) 5/401 1.2 (0.2, 2.3) 9/401 2.2 (0.8, 3.7)
Lupus 4/401 1.0 (0.0, 2.0) 1/401 0.2 (0.0, 0.7) 5/401 1.2 (0.2, 2.3)

Neurologic
Sleep Disorder 8/400 2.0 (0.6, 3.4) 47/400 11.8 (8.6, 14.9) 56/401 14.0 (10.6, 17.4)
Movement Disorder 0/401 0.0 - 3/401 0.7 (0.0, 1.6) 3/401 0.7 (0.0, 1.6)
Dementia 0/401 0.0 - 9/401 2.2 (0.8, 3.7) 9/401 2.2 (0.8, 3.7)

Ophthalmologic
Cataracts 11/402 2.7 (1.1, 4.3) 26 6.5 (4.1, 8.9) 37 9.2 (6.4, 12.0)

Psychiatric or Mental Health
Alcoholism 31/399 7.8 (5.1, 10.4) 14/399 3.5 (1.7, 5.3) 45/399 11.3 (8.2, 14.4)
Drug Addiction 19/398 4.8 (2.7, 6.9) 11/398 2.8 (1.1, 4.4) 30/398 7.5 (4.9, 10.4)
Anorexia 3/399 0.8 (0.0, 1.6) 0/399 0.0 - 3/399 0.8 (0.0, 1.6)
Bulimia 1/398 0.3 (0.0, 0.7) 0/399 0.0 - 1/399 0.3 (0.0, 0.7)
Other Eating Disorder 0/399 0.0 - 3/399 0.8 (0.0, 1.6) 3/399 0.8 (0.0, 1.6)
Anxiety 20/398 5.0 (2.9, 7.2) 78/398 19.6 (15.7, 23.5) 98/398 24.6 (20.4, 28.9)
Obsessive Compulsive Disorder 10/397 2.5 (1.0, 4.1) 7/397 1.8 (0.5, 3.1) 17/397 4.3 (2.3, 6.3)
Panic Attacks 10/397 2.5 (1.0, 4.1) 44/397 11.1 (8.0, 14.2) 55/398 13.8 (10.4, 17.2)
Post-Traumatic Stress Disorder 6/398 1.5 (0.3, 2.7) 24/398 6.0 (3.7, 8.4) 31/399 7.8 (5.1, 10.4)
Depression 25/396 6.3 (3.9, 8.7) 83/396 21.0 (16.9, 25.0) 109/397 27.5 (23.0, 31.9)
Bipolar Disorder 13/395 3.3 (1.52, 5.1) 23/395 5.8 (3.5, 8.1) 38/397 9.6 (6.7, 12.5)
ADD/ADHD 24/400 6.0 (3.7, 8.3) 18/400 4.5 (2.5, 6.5) 42/400 10.5 (7.5, 13.5)
Narcolepsy 0/399 0.0 - 3/396 0.8 (0.0, 1.6) 3/399 0.8 (0.0, 1.6)
Psychosis 3/398 0.8 (0.0, 1.6) 2/398 0.5 (0.0, 1.2) 5/398 1.3 (0.2, 2.4)
Schizophrenia 2/400 0.5 (0.0, 1.2) 2/400 0.5 (0.0, 1.2) 4/400 1.0 (0.0, 2.0)
Autism 1/400 0.3 (0.0, 0.7) 0/400 0.0 - 1/400 0.0 (0.0, 0.7)

Respiratory
Asthma 20/404 5.0 (2.8, 7.1) 9/404 2.2 (0.8, 3.7) 29/404 7.2 (4.7, 9.7)
Emphysema 3/404 0.7 (0.0, 1.6) 1/404 0.2 (0.0, 0.7) 4/404 1.0 (0.0, 2.0)
COPD 2/404 0.5 (0.0, 1.2) 6/404 1.5 (0.3, 2.7) 8/404 2.0 (0.6, 3.3)
Chronic Bronchitis 9/402 2.2 (0.8, 3.7) 7/402 1.7 (0.5, 3.0) 16/402 4.0 (2.1, 5.9)
Hay Fever 32/402 8.0 (5.3, 10.6) 2/402 0.5 (0.0, 1.2) 34/402 8.5 (5.7, 11.2)

Cancer
Skin Cancer 2/403 0.5 (0.0, 1.2) 7/403 1.7 (0.5, 3.0) 9/403 2.2 (0.8, 3.7)
Other Cancer 5/403 1.2 (0.2, 2.3) 11/403 2.7 (1.1, 4.3) 16/403 4.0 (2.1, 5.9)

X = number of patients reporting comorbidity, N = total number of patients with and without the comorbidity; CI = confidence interval

Sample size (N) varies due to missing data about specific medical comorbidities and onset (before, same time, or after TBI)

Abbreviations: ADD/ADHD = Attention Deficit Disorder / Attention Deficit Hyperactivity Disorder; COPD = Chronic Obstructive Pulmonary Disorder