Table 4:

Percent of Cases Developing the 10 Most Frequent Medical Comorbidities in the Decade after TBI by Age Cohort

	Same Time / After TBI
	< 50 Years at 10 Year FU			≥ 50 Years at 10 Year FU			≥ 50 vs. < 50 Years Comparison
	X / N	Percent	95% CI	X / N	Percent	95% CI	OR	95% CI	p-value
Back Pain	47/209	22.5	(16.8, 28.2)	40/190	21.1	(15.2, 26.9)	0.92	(0.57, 1.48)	0.7288
Depression	48/207	23.2	(17.4, 29.0)	35/189	18.5	(12.9, 24.1)	0.75	(0.46, 1.23)	0.2549
Hypertension	32/207	15.5	(10.5, 20.4)	47/187	25.1	(18.9, 31.4)	1.84	(1.11, 3.03)	0.0175
Anxiety	40/208	19.2	(13.8, 24.6)	38/190	20.0	(14.3, 25.7)	1.05	(0.64, 1.72)	0.8469
Fractures (Hip/Wrist/Spine)	41/209	19.6	(14.2, 25.0)	32/191	16.8	(11.4, 22.1)	0.82	(0.49, 1.37)	0.4594
High Blood Cholesterol	26/210	12.4	(7.9, 16.9)	42/188	22.3	(16.3, 28.3)	2.04	(1.19, 3.48)	0.0092
Sleep Disorder	20/210	9.5	(5.5, 13.5)	27/190	14.2	(2.5, 9.2)	1.57	(0.85, 2.91)	0.1485
Panic Attacks	33/208	15.9	(10.9, 20.9)	11/189	5.8	(2.5, 9.2)	0.33	(1.16, 0.67)	0.0022
Osteoarthritis	14/210	6.7	(3.3, 10.1)	24/190	12.6	(7.9, 17.4)	2.02	(1.01, 4.04)	0.0454
Diabetes	9/211	4.3	(1.5, 7.0)	26/191	13.6	(8.7, 18.5)	3.54	(1.61, 7.76)	0.0016

X = number of patients reporting comorbidity, N = total number of patients with and without the comorbidity; CI = confidence interval; OR = odds ratio