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. Author manuscript; available in PMC: 2020 Jul 1.
Published before final editing as: J Endocrinol. 2019 Jan 1:JOE-18-0355.R2. doi: 10.1530/JOE-18-0355

Figure 8.

Figure 8

An intermediate level of Nrf2 activation in NOD mice also shows protection. (A) Kaplan-Meier survival curves showing the percentage of diabetes-free NOD::Keap1+/+ (n=11) and NOD::Keap1FA/FA (n=12) mice. Diabetes was defined as a blood glucose level >250 mg/dL after consecutive biweekly measurements. (B, C) Blood glucose levels (B) and body weights (C) in the NOD::Keap1+/+ (n=11) and NOD::Keap1FA/FA (n=10) mice at 22 weeks of age. The bar represents the median. Log-rank tests for the Kaplan-Meier survival curves (A) and Student’s t-test (B and C) were performed. *P<0.05.