TABLE 1.
Individual subject demographics, serum retinol concentrations, and liver weights1
ID | Sex, M/F | Age, y | Body weight, kg | BMI, kg/m2 | [ROH], µmol/L | Liver weight, g |
---|---|---|---|---|---|---|
US1 | M | 47 | 72.6 | 29.3 | 2.34 | 1375 |
US2 | F | 55 | 57.7 | 25.7 | 1.64 | 1196 |
US3 | F | 44 | 82.3 | 30.7 | 1.44 | 1494 |
US4 | F | 70 | 54.5 | 22.0 | 1.41 | 1192 |
US5 | F | 57 | 60.4 | 27.9 | 2.06 | 1213 |
US6 | M | 68 | 79.5 | 25.9 | 1.41 | 1519 |
US7 | F | 67 | 65.8 | 26.6 | 1.85 | 1309 |
CH1 | M | 50 | 59.8 | 23.9 | 1.40 | 1251 |
CH2 | M | 60 | 63.8 | 21.6 | 1.35 | 1347 |
CH3 | F | 57 | 77.0 | 28.6 | 1.10 | 1446 |
CH4 | F | 51 | 56.9 | 23.7 | 0.932 | 1208 |
CH5 | F | 55 | 77.4 | 29.9 | 0.850 | 1436 |
CH6 | M | 53 | 72.0 | 30.0 | 1.58 | 1359 |
1Shown are subject characteristics for US (US1–7) and Chinese subjects (CH1–6), a subset of the individuals studied by Tang et al. (17) and Wang et al. (18), respectively. Retinol concentrations [ROH] are means based on analysis of the 19 serum samples collected from 3 h to 52 d after administration of [2H8]retinyl acetate, as described in (10). Estimated liver weights were calculated as body surface area × 772 (23).