TABLE 1.
All (n = 18) | FTO homozygous minor allele (AA) (n = 9) | FTO homozygous major allele (TT) (n = 9) | AA vs. TT mean difference (95% CI) | ES | |
---|---|---|---|---|---|
Age, y | 28.5 ± 9.8 | 28.5 ± 9.6 | 28.4 ± 10.5 | 0.1 (−9.9, 10.2) | 0.01 |
Height, m | 1.78 ± 0.06 | 1.78 ± 0.07 | 1.78 ± 0.05 | −0.002 (−0.06, 0.06) | 0.03 |
Body mass, kg | 85.5 ± 16.0 | 85.7 ± 14.2 | 85.3 ± 18.5 | 0.4 (−16.1, 16.9) | 0.03 |
BMI, kg/m2 | 27.0 ± 5.0 | 27.1 ± 4.7 | 26.8 ± 5.6 | 0.2 (−4.9, 5.4) | 0.05 |
Body fat percentage, % | 20.2 ± 9.1 | 18.9 ± 9.1 | 21.4 ± 9.5 | −2.6 (−11.8, 6.7) | 0.27 |
Fat-free mass, kg | 67.1 ± 7.8 | 68.7 ± 8.8 | 65.5 ± 6.8 | 3.1 (−4.7, 11.0) | 0.40 |
Values are means ± SDs, n = 18 healthy men (9 AA, 9 TT). ES, standardized effect size (mean difference); FTO, fat mass and obesity associated gene.