Table 3.
HRs (95% CIs) for the association between tea consumption and cancer risk by tobacco smoking and excessive alcohol consumption among 455,981 participants
| Less than weekly | Weekly | Daily | P interaction | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤ 2 g | 2.1–4.0 g | > 4.0 g | |||||||||
| Cases | HR | Cases | HR (95%CI) | Cases | HR (95%CI) | Cases | HR (95%CI) | Cases | HR (95%CI) | ||
| All cancers | < 0.001 | ||||||||||
| Smoking (−) and excessive alcohol consumption (−) | 11,082 | 1.00 | 840 | 1.07 (0.99, 1.15) | 1183 | 0.99 (0.93, 1.06) | 975 | 1.04 (0.97, 1.12) | 447 | 1.03 (0.93, 1.13) | |
| Smoking (+) or excessive alcohol consumption (+) | 3390 | 1.00 | 653 | 1.00 (0.92, 1.09) | 1258 | 1.06 (0.99, 1.14) | 1354 | 1.12 (1.04, 1.20) | 1470 | 1.25 (1.17, 1.34) | |
| Lung cancer | 0.010 | ||||||||||
| Smoking (−) and excessive alcohol consumption (−) | 1488 | 1.00 | 114 | 1.06 (0.87, 1.30) | 180 | 0.96 (0.81, 1.14) | 138 | 0.95 (0.78, 1.16) | 68 | 1.08 (0.84, 1.40) | |
| Smoking (+) or excessive alcohol consumption (+) | 790 | 1.00 | 134 | 0.89 (0.74, 1.07) | 323 | 1.10 (0.96, 1.27) | 375 | 1.23 (1.08, 1.42) | 436 | 1.51 (1.33, 1.72) | |
| Stomach cancer | 0.702 | ||||||||||
| Smoking (−) and excessive alcohol consumption (−) | 965 | 1.00 | 62 | 1.06 (0.82, 1.39) | 67 | 0.81 (0.63, 1.05) | 54 | 0.86 (0.65, 1.15) | 47 | 1.46 (1.07, 1.99) | |
| Smoking (+) or excessive alcohol consumption (+) | 491 | 1.00 | 111 | 1.10 (0.88, 1.36) | 172 | 0.90 (0.75, 1.09) | 167 | 0.87 (0.72, 1.05) | 230 | 1.15 (0.97, 1.37) | |
| Colorectal cancer | 0.774 | ||||||||||
| Smoking (−) and excessive alcohol consumption (−) | 1141 | 1.00 | 95 | 1.17 (0.94, 1.45) | 144 | 1.16 (0.96, 1.40) | 100 | 1.06 (0.85, 1.33) | 52 | 1.08 (0.81, 1.45) | |
| Smoking (+) or excessive alcohol consumption (+) | 290 | 1.00 | 74 | 1.17 (0.90, 1.53) | 110 | 1.00 (0.78, 1.27) | 116 | 1.01 (0.80, 1.28) | 145 | 1.22 (0.98, 1.52) | |
| Liver cancer | 0.895 | ||||||||||
| Smoking (−) and excessive alcohol consumption (−) | 758 | 1.00 | 52 | 0.93 (0.69, 1.24) | 82 | 0.94 (0.73, 1.21) | 73 | 1.00 (0.77, 1.31) | 33 | 1.08 (0.75, 1.55) | |
| Smoking (+) or excessive alcohol consumption (+) | 385 | 1.00 | 86 | 1.05 (0.82, 1.34) | 134 | 1.02 (0.82, 1.27) | 150 | 1.06 (0.86, 1.32) | 121 | 0.91 (0.73, 1.14) | |
HR indicates hazard ratio; CI, confidence interval
Multivariable model was adjusted for the same set of covariates as in the Table 2
Case/person-years information was listed in the Appendix Table 5
Smoking (−): nonsmoking; (+): current smoking
Excessive alcohol consumption (−): less than daily or < 15 g/d of pure alcohol consumption; (+): ≥ 15 g/d of pure alcohol consumption