Table 3.
Correlations of the CII with lung function and exercise performance at baseline in the investigated SSc patients.
| Parameter | Unadjusted | Adjusted* |
|---|---|---|
| pO2 (FiO2 21%) at rest, mmHg | r = 0.28 (p = 0.01) | r = 0.19 (p = 0.09) |
| % SpO2 (at blood gas analysis) | r = 0.43 (p < 0.001) | r = 0.46 (p < 0.001) |
| FVC (% predicted) | r = 0.45 (p < 0.001) | r = 0.48 (p < 0.001) |
| TLC (% predicted) | r = 0.28 (p = 0.02) | r = 0.28 (p = 0.02) |
| RV (% predicted) | r = 0.52 (p < 0.001) | r = 0.45 (p < 0.001) |
| DLCOsb (% predicted) | r = 0.34 (p = 0.03) | r = 0.36 (p = 0.002) |
| 6MWT distance (mt) | r = 0.33 (p < 0.001) | r = 0.3 (p = 0.01) |
*Adjusted for disease duration and Body Mass Index.
CII = computerized integrated index; SSc = systemic sclerosis; pO2 = oxygen partial pressure; FiO2 = fraction of inhaled oxygen; SpO2 = oxygen saturation; FVC = forced vital capacity; TLC = total lung capacity; RV = residual volume; DLCOsb = single breath diffusion lung capacity for carbon monoxide; 6MWT = six-minute walk test; mt = meters.