. 2019 Jul 1;9:9430. doi: 10.1038/s41598-019-45636-8

Table 2.

Fourteen miRNAs were upregulated ≥2.0-fold by transient overexpression of HNRNPA2/B1 in MCF-7 cells at 48 and 72 h.

miRNA	logFC 48 h	logFC 72 h	Comments on role in breast or other cancers	Possible cellular role
miR-1266-3p	2.77	2.94	High breast tumor levels are a prognostic factor for recurrence-metastasis⁶¹	oncomiR
miR-2861	2.55	2.42	Higher expression in fulvestrant-resistant MCF-7 cells⁴³. Increased in papillary thyroid carcinomas (PTC) with lymph node metastasis⁷⁴.	Endocrine-resistance oncomiR
miR-4426	3.63	3.63	Downregulated in HER2-overexpressing MCF-7 cells⁷⁵.
miR-4667-5p	2.25	2.25	Upregulated in HER2-overexpressing MCF-7 cells⁷⁵
miR-4739	3.03	3.03	Increased by si-CTNNB1 (β-catenin) in gastric cancer (GC) cells, implying a tumor suppressive function in GC⁷⁶.	Tumor suppressor
miR-6087	2.15	2.03	Downregulated in Adriamycin-resistant MCF-7 cells⁷⁷.
miR-6088	2.63	2.42	Increased by the natural sweetener steviol in HCT-116 cells⁷⁸.
miR-6762-5p	2.95	2.41	No references found
miR-6771-5p	2.49	2.26	No references found
miR-6801-3p	3.19	3.03	No references found
miR-6803-5p	2.45	2.00	No references found
miR-6805-3p	2.79	2.40	Increased by 1 nM progestin R5020 in T47D, BT474, and ZR-75-1 BCa cells, but its role was not examined⁷⁹
miR-7107-5p	2.13	3.03	Higher breast tumor expression levels associated with acquired resistance to chemotherapy⁶³.	oncomiR chemo-resistance
miR-762	3.23	2.41	promotes BrCa cell proliferation & invasion by targeting IRF7⁸⁰. Directly targets tumor suppressor MEN1 in ovarian cancer and promotes metastasis⁸¹.	oncomiR

miRNAs are sorted by name. The log fold change (logFC) is the average of 6 biological replicate samples and all are statistically significant as indicated by the p ≤ 0.05. The apparent cellular role is based on publications cited related to breast or other cancers as indicated as found in PubMed and Google Scholar.