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. 2019 Jun 25;10:770. doi: 10.3389/fphys.2019.00770

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Copyright © 2019 Drescher, Weiskirchen, Fülöp, Hopf, de San Román, Huesgen, de Bruin, Bongiovanni, Christ, Tolba, Trautwein and Kroy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of individual lipid concentration and distribution by high resolution mass spectrometry imaging. Lipid composition in the liver of animals receiving the WD-Std, WD-NTF or WD-Corn compositions were assessed by mass spectrometry imaging (n = 4). Exemplary images of panel (A) phosphatidylcholine 36:4 (PC(36:4)) and (B) TG 56:5 (TG(56:5)) and corresponding quantified signal intensities of panel (C) PC(36:4) and (D) TG(56:5) are shown. Among all observed lipid species, no significantly different accumulation was found.