Table 1.
Feature | Childhood asthma | Adult asthma |
---|---|---|
Variable Phenotypes | Yes | Yes |
Symptoms | Age 0–6 years: Cough, wheezing, acute episodes of dyspnea and increased work of breathing Age 6–11 years: cough, wheezing, dyspnea or cough with exertion Age 11–18 years: cough, wheezing, dyspnea, dyspnea on exertion, chest tightness, chest pain |
Shortness of breath, wheeze, chest tightness and cough. Allergic bronchopulmonary aspergillosis: Above symptoms plus sputum production. Aspirin exacerbated respiratory disease: Above symptoms plus nasal polyps and sensitivity to aspirin. |
Sex predominance | Males < 10 years | Females |
Remission | Common | Rare |
Factors associated with severity | Asthma duration, medication use, lung function, neutrophilic phenotype, low socioeconomic status, racial/ethnic minorities | IgE, FeNO, eosinophilia, obesity, smoking, low socioeconomic status |
Mortality | Rare | Uncommon |