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Study design and groups.
| Treatment group | Experimental biological product and (estimated dose) | No. of animals | Route of administration | Challenge |
|---|---|---|---|---|
| T01 | PBS (Negative control) | 8 | s/c | B. bronchiseptica |
| T02 | Bronchicine CAe (Positive control) | 8 | s/c | B. bronchiseptica |
| T03 | BbBG – 7 (~1 × 107 BG particles) | 8 | s/c | B. bronchiseptica |
| T04 | BbBG – 5 (~1 × 105 BG particles) | 8 | s/c | B. bronchiseptica |
PBS, phosphate buffer saline; BbBG, B. bronchiseptica Bacterial Ghosts; s/c, sub cutaneous.
