Table 5.
Factor | Xenodiagnosis Resultsa | ||
---|---|---|---|
Negative | Positive | P Value | |
Visceral leishmaniasis patients | N = 5 | N = 10 | |
Age | |||
Mean [SD] | 22 [2.9] | 32.1 [13.7] | …b |
Median [IQR] | 23 [20, 24] | 31.5 [19, 45] | .33 |
Female Sex n (%) | 3 (60.0) | 4 (40.0) | .61 |
BMI (kg/m2) | |||
Mean [SD] | 15.0 [1.8] | 18.0 [2.0] | …b |
Median [IQR] | 15.2 [13.8, 15.8] | 18.4 [16.4, 18.7] | .03 |
Spleen size (cm below costal margin) | |||
Mean [SD] | 12.0 [7.4] | 7.1 [5.9] | …b |
Median [IQR] | 9.0 [7, 16] | 5.5 [3, 12] | .14 |
Liver size (cm below costal margin) | |||
Mean [SD] | 7.0 [3.1] | 2.5 [3.9] | …b |
Median [IQR] | 6.0 [6, 9] | 0.75 [0, 3] | .04 |
Blood positive by qPCR | 3 (60.0) | 10 (100) | .10 |
Parasite load (per mL blood) | |||
Mean [SD] | 13.5 [20.3] | 232.9 [310.1] | …b |
Median [IQR] | 4.2 [0, 15.4] | 93.3 [40.5, 321.6] | .02 |
Log10 parasite loadC | |||
Mean [SD] | 0.72 [0.75] | 2.00 [0.64] | …b |
Median [IQR] | 0.72 [0, 1.22] | 1.97 [1.61, 2.51] | .01 |
We report both the median + IQR and mean + SD to provide some indication of the skew of the distribution.
Abbreviations: IQR, interquartile range; SD, standard deviation.
aComposite results by microscopy and/or polymerase chain reaction in sand flies from any of the xenodiagnosis experiments.
bbMean + SD shown to provide indication of skew of the distribution; p value based on Wilcoxon rank sum test.
CParasite load per milliliter blood transformed as log10(parasite load + 1) to account for zero parasite loads.