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. 2018 Oct 24;69(2):251–258. doi: 10.1093/cid/ciy891

Table 5.

Factors Associated With Positive Xenodiagnosis Results Among 15 Visceral Leishmaniasis Patients: Mymensingh, Bangladesh, 2017

Factor Xenodiagnosis Resultsa
Negative Positive P Value
Visceral leishmaniasis patients N = 5 N = 10
Age
 Mean [SD] 22 [2.9] 32.1 [13.7] …b
 Median [IQR] 23 [20, 24] 31.5 [19, 45] .33
Female Sex n (%) 3 (60.0) 4 (40.0) .61
BMI (kg/m2)
 Mean [SD] 15.0 [1.8] 18.0 [2.0] …b
 Median [IQR] 15.2 [13.8, 15.8] 18.4 [16.4, 18.7] .03
Spleen size (cm below costal margin)
 Mean [SD] 12.0 [7.4] 7.1 [5.9] …b
 Median [IQR] 9.0 [7, 16] 5.5 [3, 12] .14
Liver size (cm below costal margin)
 Mean [SD] 7.0 [3.1] 2.5 [3.9] …b
 Median [IQR] 6.0 [6, 9] 0.75 [0, 3] .04
Blood positive by qPCR 3 (60.0) 10 (100) .10
Parasite load (per mL blood)
 Mean [SD] 13.5 [20.3] 232.9 [310.1] …b
 Median [IQR] 4.2 [0, 15.4] 93.3 [40.5, 321.6] .02
Log10 parasite loadC
 Mean [SD] 0.72 [0.75] 2.00 [0.64] …b
 Median [IQR] 0.72 [0, 1.22] 1.97 [1.61, 2.51] .01

We report both the median + IQR and mean + SD to provide some indication of the skew of the distribution.

Abbreviations: IQR, interquartile range; SD, standard deviation.

aComposite results by microscopy and/or polymerase chain reaction in sand flies from any of the xenodiagnosis experiments.

bbMean + SD shown to provide indication of skew of the distribution; p value based on Wilcoxon rank sum test.

CParasite load per milliliter blood transformed as log10(parasite load + 1) to account for zero parasite loads.