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. 2018 Oct 11;69(2):306–315. doi: 10.1093/cid/ciy861

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© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

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Figure 2. — The pretravel health encounter (PHE) offers better value if more travelers are unvaccinated at baseline or if more eligible travelers receive measles-mumps-rubella (MMR) vaccination at PHE. The figure shows a 2-way sensitivity analyses of the value of PHE, compared with no PHE, while modifying Risk_exposure (y-axis) and the percentage of travelers unvaccinated at baseline (x-axis, A) or receiving vaccination at PHE (x-axis, B). A white X marks the base case. Horizontal lines represent the risk of exposure to measles while traveling to different continents or hot spots, from the highest (top) to lowest (bottom) risk of exposure. (A) PHE offers better value (yellow or orange) or is cost-saving (green) when Risk_exposure is high (top) or when more travelers are unvaccinated at baseline (right). (B) PHE offers better value or is cost-saving if more MMR-eligible travelers are vaccinated at PHE (right), especially for travelers whose destinations have a higher Risk_exposure (top). PHE is never preferred, regardless of the risk of measles exposure, when no MMR-eligible travelers receive the MMR vaccine during PHE (black). Abbreviations: ICER, incremental cost-effectiveness ratio, in US$ per measles case averted; MMR, measles-mumps-rubella; PHE, pretravel health encounter.